Early diagnosis of sepsis is a challenge for physicians because the success or failure of patient evolution is related to the fast recognition of the syndrome presence and the prompt therapeutic approach. Several indicators are proposed as auxiliary indicators of sepsis. This text will emphasize the participation of leukocytes in the inflammatory/infectious process, especially the role of segmented neutrophils and their precursors. Some granulocyte-related markers that can be easily obtained on a routine blood count when performed on Sysmex hematology analyzers will be presented.

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